Publications 2007

Zhou, T., L. Xu, B. Dey, A.J. Hessell, D. Van Ryk, S-H. Xiang, X. Yang, M-Y. Zhang, M.B. Zwick, J. Arthos, D.R. Burton , D.S. Dimitrov, J. Sodroski, R. Wyatt, G.J. Nabel, P. D. Kwong. (2007) Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature, 445 :732-737.

Nelson, J.D., F.M. Brunel, R. Jensen, E.T. Crooks, R.M.F. Cardoso, M. Wang, A. Hessell, I.A. Wilson, J.M. Binley, P.E. Dawson, D.R. Burton , M.B. Zwick. (2007) In vitro affinity maturation of Z13, a broadly neutralizing antibody against human immunodeficiency virus type 1 (HIV-1) gp41. J. Virol. 81:4033-4043.

Pantophlet, R., R.O. Aguilar-Sino, T. Wrin, L.A. Cavacini, D.R. Burton. (2007) Analysis of the neutralization breadth of the anti-V3 antibody F425-B4e8 and re-assessment of its epitope fine specificity by scanning mutagenesis. Virology, 364: 441-453.

Dhillon, A.K., H. Donners, R. Pantophlet, W.E. Johnson, J.M. Decker, G.M. Shaw, F-H. Lee, D.D. Richman, R.W. Doms, G. Vanham, D.R. Burton. (2007) Dissecting the neutralizing antibody specificities of broadly neutralizing sera from HIV-1 infected donors. J. Virol. , 81: 6548-6562.

Crooks, E.T., P.L. Moore, M. Franti, C.S. Cayanan, P. Zhu, P. Jiang, R. deVries, C. Wiley, I. Zharkikh, N. Sch ├╝lke, K.H. Roux, D.C. Montefiori, D.R. Burton , J.M. Binley. (2007) A Comparative Immunogenicity Study of HIV-1 Virus-Like Particles Bearing Various Forms of Envelope Proteins, Particles Bearing no Envelope and soluble monomeric gp120. Virology, 366 :245-262.

Law, M., R.M.F. Cardoso, I.A. Wilson, D.R. Burton. (2007) Antigenic and immunogenic study of membrane-proximal external region-grafted gp120 antigens by a DNA prime-protein boost immunization strategy. J. Virol., 81: 4272-4285.

Oswald W.B., T.W. Geisbert, K.J. Davis, J.B. Geisbert, N.J. Sullivan, P.B. Jahrling, P.W.H.I. Parren, D.R. Burton. (2007) Neutralizing antibody fails to impact the course of Ebola virus infection in monkeys, PLoS Pathogens, 3 :62-66.

Bowley, D.R., A.F. Labrijn, M.B. Zwick, D.R. Burton. (2007) Antigen selection from an HIV-1 immune antibody library displayed on yeast yields many novel antibodies compared to selection from the same library displayed on phage, Protein Engineering Design & Selection (PEDS) , 20: 81-90.

Scanlan, C.N., G.E. Ritchie, K. Baruah, D. Harvey, B.B. Singer, L. Lucka, M.D. Crispin, M.R. Wormald, P. Wentworth, Jr., N. Zitzmann, P.M. Rudd, D.R. Burton , R.A. Dwek. (2007) Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralizing, HIV-1 specific antibody. J. Mol. Biol., 372 :16-22.

Mantis, N.J., A.J. Hessell, J. Palaia, S. Mahta, Z. Zhu, B. Corthesy, M.R. Neutra, D.R. Burton , E.N. Janoff. (2007) Inhibition of HIV-1 infectivity and epithelial cell transfer by a recombinant human IgA to envelope gp120. J. Immunology, 179: 3144-315.

Hessell, A.J., L. Hangartner, M. Hunter, C.E.G. Havenith, F.J. Beurskens, J.M. Bakker, C.M.S. Lanigan, G. Landucci, D.N. Fothal, P.W.H.I. Parren, P.A. Marx, D.R. Burton. (2007) The Fc receptor but not complement binding is important in antibody protection against HIV. Nature, 449: 101-104.

Scherer, E.M., M.B. Zwick, L. Teyton, D.R. Burton. (2007) Difficulties in eliciting broadly neutralizing anti-HIV antibodies are not explained by cardiolipin autoreactivity. AIDS. 21:2131-2139.

Burton, D.R., I.A. Wilson. (2007) Square dancing antibodies. Science, 317: 1507-1508.

Law, M., T. Maruyama, J. Lewis, E. Giang, A.W. Tarr, Z. Stamataki, P. Gastaminza, F.V. Chisari, I.M. Jones, R.I. Fox, J.K. Ball, J.A. McKeating, N.M. Kneteman, D.R. Burton. (2007) Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge. Nature Medicine, 14: 26-27.

Zwick, M.B., Burton, D.R. (2007) HIV-1 neutralization: mechanisms and relevance to vaccine design. Current HIV Research, 5 :608-624.